TO STUDY EARLY NEURO-RETINAL DEGENERATION IN TYPE 2 DIABETES & COMPARE IT WITH NORMAL SUBJECTS WITH SPECTRAL DOMAIN OCT

Abstract

Aim:

The aim of the following study is to evaluate the  Central macular thickness (CMT), retinal nerve fiber layer (RNFL) and ganglion cell complex (GCC) thickness in patients with type 2 diabetes mellitus (DM) and compare it with normal subjects of same age groups..

Materials and Methods:

Central macular thickness (CMT), Retinal nerve fibre layer ( RNFL) and Ganglion cell complex ( GCC) thickness were measured in 180 eyes using spectral domain optical coherence tomography. The values of participants with DM were compared to controls. Diabetic patients were collected in Groups 1, 2 and 3. Group 1 = 50 eyes who had no diabetic retinopathy (DR); Group 2 = 50 eyes who had mild nonproliferative DR and Group 3 = 40 eyes who had moderate non-proliferative DR. The 40 healthy( non-diabetic ) eyes collected in Group 4. Analysis of variance test  used for statistical analysis.

Results:

The values of CMT,  RNFL and GCC in the type 2 diabetes were thinner than controls and this difference was statistically significant.

Conclusions:

This study showed that there is a significant loss of CMT, RNFL and GCC in patients with type 2 diabetes.