TO STUDY EARLY NEURO-RETINAL DEGENERATION IN TYPE 2 DIABETES & COMPARE IT WITH NORMAL SUBJECTS WITH SPECTRAL DOMAIN OCT
Abstract
The aim of the following study is to evaluate the Central macular thickness (CMT), retinal nerve fiber layer (RNFL) and ganglion cell complex (GCC) thickness in patients with type 2 diabetes mellitus (DM) and compare it with normal subjects of same age groups..
Materials and Methods:
Central macular thickness (CMT), Retinal nerve fibre layer ( RNFL) and Ganglion cell complex ( GCC) thickness were measured in 180 eyes using spectral domain optical coherence tomography. The values of participants with DM were compared to controls. Diabetic patients were collected in Groups 1, 2 and 3. Group 1 = 50 eyes who had no diabetic retinopathy (DR); Group 2 = 50 eyes who had mild nonproliferative DR and Group 3 = 40 eyes who had moderate non-proliferative DR. The 40 healthy( non-diabetic ) eyes collected in Group 4. Analysis of variance test used for statistical analysis.
Results:
The values of CMT, RNFL and GCC in the type 2 diabetes were thinner than controls and this difference was statistically significant.
Conclusions:
This study showed that there is a significant loss of CMT, RNFL and GCC in patients with type 2 diabetes.
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