A COMPARISON OF POST-OPERATIVE ANALGESIA BETWEEN INTRATHECAL NALBUPHINE WITH LEVOBUPIVACAINE 0.5% AND INTRATHECAL LEVOBUPIVACAINE 0.5% ALONE IN INTRA ABDOMINAL SURGERIES

Abstract

BACKGROUND AND OBJECTIVES:
Regional anaesthesia has emerged as an important
technique, with rapid onset of action and good muscle
relaxation and relatively simplicity of administration.
Intrathecal anaesthesia is widely used regional anaesthesia
technique with effective sensory and motor blockade.
Racemic bupivacaine is the most frequently used local
anaesthetic agent for intrathecal anaesthesia.ere are also
undesirable side effects associated with bupivacaine such as
cardiotoxicity, CNS toxicity as well as prolonged motor
blockade. Levobupivacaine , a pure S(-) enantiomer of
bupivacaine , has emerged in recent years as an alternative
for regional anaesthesia with desirable properties such as low
cardio toxicity , less motor blockade.