COMPARISON OF THE EFFICACY OF CHLORHEXIDINE GLUCONATE VERSUS POVIDONE IODINE AS PREOPERATIVE SKIN PREPARATION FOR THE PREVENTION OF SURGICAL SITE INFECTIONS

Dr. T. Srinivasan, Dr. Karthick Balaji

Abstract


Background: Infections that occur in the wound created by an invasive surgical procedure are generally referred as
surgical site infections (SSIs). The microorganisms that cause SSIs are usually derived from the patient (endogenous
infection), being present on their skin or from an opened viscous. Preoperative skin preparation of the surgical site using
appropriate antiseptic products is one of the important interventions to prevent SSIs. SSIs can double the length of time a
patient stays in hospital and thereby increase the costs of health care. The aim of this study To compare efficacy of
Povidone Iodine and Chlorhexidine Gluconate with help of sterile saline swab culture of SSIs.
Methodology: Patients were randomly divided in Group I & Group II each group having equal number of patients
undergoing elective clean & clean-contaminated surgeries. The pre operative skin preparation is done with povidone
iodine IP 5% w/v in group-I & chlorhexidine gluconate 5% v/v in aqueous base in group II. In both the groups sterile
saline swab culture were taken from the incision site pre-painting as well as post-painting.
Results: A total of two hundred surgical cases included in study and age ranges from 14 to 80 years and male:female
ratio was 1.24 :1 and bacterial growth in prepainting period in povidone iodine group was81.70% while in chlorhexidine
group is 99.15% which is statistically insignificant and in postpainting period in povidone iodine group 4.8% while in
chlorhexidine group is 1.6% which is statistically significant.
Conclusion: Hence it can be safely concluded that chlorhexidine aquaous was associated with reduced risk of
postoperative SSI in clean and clean-contaminated surgery when compared to Povidone Iodine. Further studies should
evaluate the effectiveness of CHG versus PI in reducing SSI across contaminated surgery.


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