PREVALENCE OF PERIPHERAL NEUROPATHY IN CHRONIC KIDNEY DISEASE: A PROSPECTIVE STUDY

Dr Tikamchand More, Dr. Ranvir Singh Yadav

Abstract


Background: Patients with chronic kidney disease (CKD) are frequently afflicted with neurological complications.
These complications can potentially affect both the central and peripheral nervous systems. These conditions have
significant impact not only on patient morbidity but also on mortality risk through a variety of mechanisms.
Aims and Objectives: To study prevalence of peripheral neuropathy in CKD patients.
Materials and Methods: Hundred CKD patients having age >18 years were studied at Department of general
medicine, Gandhi Medical College, & associated Hospitals (Hamidia Hospital) Bhopal from 2017 to 2020. Viral markers,
CBC, fasting and post prandial blood sugar, serum electrolytes, serum urea and creatinine, liver function test, serum
profile, coagulation profile, ECG, chest X ray and Nerve conduction studies were performed and results were recorded.
Results: CKD was more prevalent in young age group of 20-30 years (29%) followed by 31 to 40 (22%), 41 to 50(20%), 51
to 60(20%) and in male patients (65%). Majority had stage 4 CKD followed by stage 5 and stage 3. Nerve Conduction
Study of findings reveals that prevalence of axonal motor neuropathy in upper limbs was in 12%, axonal sensor motor
neuropathy in upper limbs was 5%, axonal sensory neuropathy in lower limbs was 10%, axonal sensory motor
neuropathy in lower limbs was 21%, demyelination sensory neuropathy in upper limbs was 5% and mixed sensor motor
neuropathy in both lower limbs was 14%. Conclusion: Neurological problems are common in CKD which cause
significant morbidity and mortality. Early detection and management of these conditions in mild CKD is very important
to limit their impact at later stages.


Keywords


nerve conduction study, sensory motor neuropathy, mortality

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