ACUTE POISONING AT THE CRITICAL CARE AND TOXICOLOGY UNIT OF THE JOSEPH RAVOAHANGY ANDRIANAVALONA TEACHING HOSPITAL, ANTANANARIVO, MADAGASCAR

Razafindraibe Faneva Angelo Parfait, Rakotomavo Falihery Albertin, Ramarolahy Rija Niaina, Rakotoarison Ratsaraharimana na Cathérin, Raveloson Nasolotsiry Enintsoa

Abstract


BACKGROUND : Acute poisoning (APP) constitutes a serious problem of public health worldwide. Our aims are to
determinate the clinical characteristics and the outcome of these intoxication and to identify the factors which are
associated to the mortality.
METHODOLOGY : A 12 month retrospective and cross-sectional study was carried out at the critical care and
toxicology unit of the Joseph Ravoahangy Andrianavalona teaching hospital, Antananarivo, Madagascar, from January to
December 2013.
RESULTS: Of the 485 cases of intoxication identified, 56.1% were male. The average age of the patients was 27.13+/-
14.28 years. Agricultural and industrial products were the most reported poisoning agents (33.5%). The muscarinic
syndrome was the most toxic syndrome observed (24.7%). Hypoglycaemia (9.3%) was the most frequent biological
abnormalities. The mortality rate was 16.7%. The factors associated with mortality were the male gender, the advanced
age, the existence of comorbidities, the suicide, the existence of co-intoxication and radiologic abnormalities (p<0.05).
CONCLUSION: The admission for acute poisoning is frequent at our unit. The mortality remains high. Multiple
interventions are needed to reduce the prevalence of intoxication.


Keywords


Acute Poisoning, Muscarinic Syndrome, Toxicology, Madagascar

Full Text:

PDF

Refbacks

  • There are currently no refbacks.