NEUROENDOCRINE CARCINOMA OF ESOPHAGUS: A RARE CASE ENTITY

Peoli Mukutawat, Sheeba Bhardwaj, Anil K Dhull, Vivek Kaushal

Abstract


Background: Neuroendocrine carcinoma of esophagus is a very rare and aggressive cancer. The incidence of neuroendocrine carcinoma of esophagus is 0.4% and 2% of all the esophageal malignancies. It is often diagnosed at advanced stage and has a poor prognosis.

Case Presentation: A 54-year-old male presented with a 3-month history of dysphagia and had been diagnosed with neuroendocrine carcinoma of esophagus. Patient was administered radical external beam radiation therapy 40 Gy in 20 fractions over 4 weeks with 2 courses of concomitant chemotherapy (injection carboplatin 450 mg and injection 5-fluoro-uracil 1000 mg), 3 weekly. The patient had symptomatic relief after treatment but after 2 months the patient’s condition deteriorated and he ultimately died 5 months after starting treatment.

Conclusion: Neuroendocrine carcinoma of esophagus is a very aggressive cancer. More research protocols & clinical trials should be explored to improvise survival in these patients.


Keywords


Neuroendocrine carcinoma, carcinoma esophagus.

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