A RETROSPECTIVE ANALYSIS OF ADVERSE DRUG REACTIONS IN HOSPITALIZED PATIENTS

Vinothkumar A K, Jegadesh R

Abstract


Adverse drug reactions are a major cause of morbidity and mortality in hospital. This study was conducted to create the awareness, communication and reporting of ADRs among health care professionals. This study is a retrospective analysis of total 29 reported ADR during a period of May 2016 to Dec 2018 in Apollo speciality Hospitals, Trichy. These ADRs were analysed based on Naranjio scoring, Hart wigs severity scale, type of reactions, body system involved causative drugs, outcome & management. The Majority of patients who had suffered from ADRs were between 18-44 yrs (48%)of age and male patients (59%) affected more than female (41%).In our Hospital Department of General medicine (41%) has reported highest number of ADR. Skin was the most affected system 69 % followed by CVS. Ranitidine (14%) shows the largest number followed by ceftriaxone (10%) and Cefoperazone (10%).Majority of the reactions are mild (97%) and occurred during IV use (93%)  All the ADRs were possible. Most of the patients were recovered (97%) early by appropriate management. The major limitation was under-reporting of ADR. It can be overcome by creating awareness to all health care professional like discussing in Drug & therapeutic committee meeting, conducting workshop.

Keywords


WHO, Central Drugs Standard Control Organization (CDSCO), Adverse drug reactions

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