TO STUDY THE PATTERN OF BACTERIAL PATHOGENS ISOLATED FROM SURGICAL SITE INFECTION AND THEIR ANTIBIOGRAM AT SMS HOSPITAL, JAIPUR

Dr. Divya Gupta, Dr. R. K. Mishra

Abstract


Background: SSIs have become a major cause of post-operative illness resulting in increased morbidity & mortality. The present study was
conducted for identification of pattern of bacterial isolates from post-surgical wound infections and providing clinicians with best antimicrobial
agents to which organisms are susceptible.
Materials & Methods: This study comprised of 130 patients underwent emergency or elective surgeries over a period of 1 year who developed
post-operative surgical site infection. The pattern of bacterial pathogens isolated from surgical site infection and their antibiogram was studied.
Results: In our study out of 130 clinically diagnosed SSI samples, 107 were culture positive and 23 samples yielded no growth. The most common
organism isolated from culture positive samples were Escherichia coli followed by gram positive cocci , Staphylococcus aureus and Pseudomonas
spp. Escherichia coli showed maximum sensitivity to Polymyxin, followed by Tigecycline, Imipenem, Amikacin, Ceftazidime and Ampicillin &
Piperacillin-Tazobactam. Staphylococcus aureus showed maximum sensitivity to Linezolid, followed by Teicoplanin & Vancomycin,
Doxycycline, Piperacillin-Tazobactam, Gentamycin and Erythromycin. Pseudomonas spp was found to be most sensitive to Gentamycin,
followed by Cotrimoxazole, Ciprofloxacin, Imipenem and Amikacin, Piperacillin-Tazobactam & Tobramycin.
Conclusion: In this study most common organisms found to be associated with SSI were Escherichia coli, Staphylococcus aureus and
Pseudomonas spp. Most of gram negative isolates were found to be sensitive to Polymyxin, Tigecycline and Imepenem. Maximum sensitivity
among gram positive isolates was seen in Linezolid, Teicoplanin and Vancomycin.


Keywords


Surgical site infection, Antimicrobial sensitivity, Escherichia coli, Staphylococcus aureus

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