Dr Shubhakara k, Dr Siddeswaraswamy P


An estimated 50 million dengue infections occur annually caused by four distinct subgroups of dengue viruses, types 1, 2, 3 and 4 (DEN 1-4) which
are RNA viruses. The genome of DEN virus encodes different gene products: C (capsid), prM (matrix), B (envelope) and seven non. structural (N -
S) proteins. NSl protein is secreted in plasma and is useful in early diagnosis. Dengue infection of humans occurs from bites of Aedes aegypti
mosquitoes. The mosquito feeds during the day and has a propensity for man-made habitats containing water. Dengue viral infection can present as
three broad clinical patterns: Classic dengue, Haemorrhagic fever and Undifferentiated fever. Clinically Liver is often enlarged and tender. There
are many articles which has reported the involvement of liver in this disease. The changes can be noted both clinically and also biochemically in
which the enzymes are quoted elevated. These features occur in both severe and non-severe dengue cases. Therefore, monitoring for warning signs
and other clinical parameters is crucial for recognising progression to critical phase. This study puts in an effort to find the hepatic profile of the
patients both clinically and biochemically so as to be useful to the practising physicians.


Clinical, Hepatic, Profile, Biochemical.

Full Text:



  • There are currently no refbacks.