FIBRINOGEN AND ISCHAEMIC HEART DISEASE

Dr. Aashka M Shah, Dr. Mahendra Shah

Abstract


Fibrinogen has been identified as an independent risk factor for Ischaemic Heart Disease (IHD) and has been associated with traditional
cardiovascular risk factors. Also, the role of elevated fibrinogen in thrombosis suggests that it may be on the causal pathway for certain risk factors
to exert their effect. The aims of present study are to estimate levels of plasma fibrinogen in patients of IHD and in controls and to evaluate its role as
a thrombotic risk factor for IHD. Plasma fibrinogen levels were determined in cases and controls by functional Clauss method. Significant
elevation in Plasma Fibrinogen levels was observed in cases as compared to controls with significant p value. (p value < 0.001). Fibrinogen is a risk
factor for CAD & it may be a useful screening tool to identify persons at increased thrombotic risk.


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