THE ROLE OF TOTAL SERUM BILIRUBIN FOR DIAGNOSIS OF ACUTE APPENDICITIS

Dr. Omar Abuelaish, Dr. Majdi Al Sodi, Dr Omar Abuzyton, Dr.mohammad Al Ajlony, Dr Hamza Qasaymeh, R.J.Al – Saada

Abstract


OBJECTIVES: To determine the role of elevated serum bilirubin in the diagnosis of acute appendicitis.
METHODS: The study conducted in the period from January to July 2008 included 58 patients admitted to surgical department at Prince Rashed
Bin Al-Hassan Hospital with clinical diagnosis of acute appendicitis. Preoperatively patient's blood was collected for serum bilirubin. The study
divided postoperatively into two study groups: Group I: 22 (37.9%) with acute appendicitis (males: 19 and females: 3. and their age ranged from 12
to 36 years), Group II: 36 (62.1%) without acute appendicitis (males: 32 and females: 4. and their age ranged from 14 to 38 years). Receiver
Operating Characteristic (ROC) curve analysis used to find the best total bilirubin cutoff value for discrimination of acute appendicitis.
RESULTS: Total serum bilirubin among patient with acute appendicitis (6.83 ± 2.9 mg/dL) was statistically higher than patient without acute
appendicitis (0.78 ± 0.67 mg/dL) P-value < 0.0001.
The total serum bilirubin cutoff value > 1.69 mg/dL showed sensitivity 100% (95% CI, 84.4-100%) and specificity 91.67% (95% CI, 77.5-98.2%).
CONCLUSION: Elevated total serum bilirubin is a good indicator and a new diagnostic tool for acute appendicitis.


Keywords


Acute Appendicitis, Total Serum Bilirubin Cutoff value

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