A COMPARATIVE STUDY OF HRV ANALYSIS IN REFLUX POSITIVE AND REFLUX NEGATIVE PATIENTS WITH ACID PEPTIC DISEASE

Dr. S. Subhashini, Dr. C. N. Angel Deepa

Abstract


The Aim of the study was to investigate a possible relationship between gastroesophageal reux and autonomic
imbalance in patients symptomatic for acid peptic disease using spectral analysis of HRV. Demographic parameters such
as Age, weight, Body Mass Index, resting heart rate and blood pressure were obtained. 24 hour pH analysis was done to identify reux positive
group. Frequency domain and time domain measures as well as demographic variables were compared between reux positive(n=23) and reux
negative group(n=24). The results revealed simultaneous decrease of LF component and increase of HF in the reux positive patients. We
demonstrated the evidence of functional ANS disturbances, which may be responsible for changing the HRV parameters of the frequency and time
domain analysis in GERD patients. The disturbances mentioned above are supposed to inuence the normal modulation of the vagaltone, which is
vital for maintaining the physiological functions of oesophageal sphincter.


Keywords


pH analysis, GERD, Frequency domain, Time domain

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