ROLE OF SERUM TSH IN PREDICTING MALIGNANCY OF THYROID SWELLINGS

Dr K. S. Chakravarty, Dr I. N. V. Thanuja

Abstract


There are many methods to predict and diagnose malignancy in thyroid nodules, of which serum TSH is a novel method.
The objective of this study is to evaluate the usefulness of serum TSH values as a predictor of malignancy in thyroid
nodules. This prospective study involved 30 patients with thyroid swellings admitted in Maharajah's institute of medical sciences, Vizianagaram.
Preoperative serum TSH values were correlated with final histopathology report.
Results: Mean preoperative TSH value in malignancy was higher compared to those with benign diseases. Incidence of malignancy increased
with higher TSH values.
Conclusion: There is a definite relationship between higher TSH levels and malignancy. TSH levels could be used as predictor in clinically
suspicious malignant thyroid swelling with a benign FNAC report. In such cases where TSH value is high, the FNAC can be relooked to confirm
the diagnosis.


Keywords


Thyroid stimulating hormone(TSH), Fine needle aspiration cytology(FNAC), Thyroid swelling, Malignancy

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