EFFICACY OF NITROGLYCERINE SPRAY ON CARDIOVASCULAR RESPONSE DURING LARYNGOSCOPY AND INTUBATION

Dr. Surendra Kumar, Dr. Ratan Kumar Choudhary, Dr. Desh Pal Singh, Dr Amit Kumar, Dr Atul Kaushik

Abstract


Laryngoscopy during intubation is associated with significant increase in pulse rate and blood pressure. The present prospective randomized comparative study conducted at Rama Medical College Hospital and Research Centre, Pilkhuwa, Hapur  aimed to assess the efficacy of Nitroglycerine spray 2 puffs (0.8mg) for attenuation of such hemodynamic stress response in patients undergoing laryngoscopy and intubation for general anaesthesia for major operation who were compared to patients receiving premedication only. The study found that the use of  Nitroglycerine spray(0.8%) administered intranasal 2 minutes before induction is associated with statistically significant  blunting of the hypertensive effect but not the tachycardia response of the cardiovascular system to laryngoscopy and intubation while under G.A.


Keywords


Nitroglycerine, General Anesthesia, Laryngoscopy and Intubation.

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