TO FIND OUT THE CORRELATION OF SERUM URIC ACID AND ASSESS THE PROGNOSTIC ROLE OF SERUM URIC ACID IN ACUTE EXACERBATION OF COPD

Dr Manak Gujrani, Dr Rajendra Saugat, Dr B. Bala Ji, Dr Gunjan Soni

Abstract


 Background and Objective:   various parameters and investigation are use for assessment of  severity  ,morbidity and mortality in acute exacerbation of COPD, In our study we explore the utility of serum uric acid level in AECOPD, Methods Hospital based descriptive type of observational study  of122 patients of  40-70 years of age group COPD exacerbation . A primary reason for admission other than AECOPD were exclude from study. Results  In COPD exacerbation  mMRC dyspnea grade increase ,the serum uric acid level increase and hospitalisation also increase with high uric acid as compared to low serum uric acid. majority(65.3%) patients of low Uric Acid group having Mean Post-bronchodilator FEV1% was 60.86±14.34while in high uric acid group(60%) patients was 31.78±10.99. Mean pH is low  and high CO2 among also high uric acid patient as compared to low serum uric acid and more Conclusion Serum Uric Acid level is be a beneficial biomarker in predicting the outcome in COPD patients hospitalized for acute exacerbation.


Keywords


Chronic Obstructive Pulmonary Disease (COPD), uric acid, hospitalisation

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