COMPARISON OF EFFICACY AND MEMORY DOMAINS OF ECT BETWEEN PULSE WIDTH OF 0.5 MS AND 1.0 MS IN PATIENTS WITH SCHIZOPHRENIA

Dr. Astik Mane, Dr. Suyog Jaiswal, Dr. Vikalp Wasnik

Abstract


Electroconvulsive therapy transformed the management of psychiatric disorders. Continuous improvement in the efficacy and cognitive outcome of ECT has been made possible by continuous research to understand the mechanism and different techniques of ECT. It was understood earlier that the components of electroconvulsive therapy were not important if seizures were induced. Numerous experiments later disclosed that the components, when changed, impact the side-effects and effectiveness of ECT. This study was conducted to evaluate the effects of brief pulse width 0.5ms and 1.0ms in patients with schizophrenia on symptoms and memory domains. In our study, patients receiving ECT were assessed on Positive and Negative Scale for Schizophrenia (PANSS), Wechsler memory scale and Autobiographical memory interview SF before ECT, the day after the 3rd ECT and the day after the 6th ECT. There were no significant differences found in the sociodemographic profile of the two groups. Significant difference was seen over time in both the groups. There were no significant differences found between the groups in time * group. We observed that over time, deterioration in memory function was present in the entire sample, but difference in the groups over time was not observed. A higher sample size would be required to further study the effects of pulse width.


Keywords


SCHIZOPHRENIA, Electroconvulsive therapy, psychiatric disorders.

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