CENTRAL OBESITY IS AN INDEPENDENT RISK FACTOR FOR INSULIN RESISTANCE IN WOMEN WITH POLYCYSTIC OVARY SYNDROME

Dr Meghana Chikhalikar, Dr Padmini Valluri

Abstract


The objective of study was to compare insulin resistance and its manifestations among obese and nonobese
PCOS women and to identify the subset of PCOS women who are most insulin resistant. Obesity
was determined based on body mass index and central obesity based on waist to hip ratio. Insulin resistance was determined
using fasting glucose to insulin ratio less than 4.5. Eighty PCOS women were included of whom 52.5% were obese. Insulin
resistance was seen in 79.5% of women with central obesity and only 27.8% of those without central obesity. Central obesity was
independent risk factor for insulin resistance.


Keywords


Insulin Resistance, Obesity, Polycystic Ovary Syndrome, Waist-to-hip Ratio

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